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主营:主营:研究并生产荧光和发光探针,信号转导研究的试剂
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当前位置: 首页 > 产品中心 > Fluorescent_dyes > AAT Bioquest/FDGlcU [Fluorescein di-beta-D-glucuronide]/14002/1 mg
商品详细AAT Bioquest/FDGlcU [Fluorescein di-beta-D-glucuronide]/14002/1 mg
AAT Bioquest/FDGlcU [Fluorescein di-beta-D-glucuronide]/14002/1 mg
AAT Bioquest/FDGlcU [Fluorescein di-beta-D-glucuronide]/14002/1 mg
商品编号: 14002
品牌: aatbio
市场价: ¥0.00
美元价: 0.00
产地: 美国(厂家直采)
公司:
产品分类: 荧光染料
公司分类: Fluorescent_dyes
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Overview
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Ex/Em(nm)490/514
MW684.55
CAS#N/A
SolventDMSO
StorageF/D/L
CategoryEnzymeDetection
HydrolyticEnzymes
RelatedReporterGeneEnzymes
iFluorRapidTests
Thebeta-glucuronidase(GUS)enzymefromE.coli(EC3.2.1.31)hasbeenwelldocumentedtoprovidedesirablecharacteristicsasaMarkergeneintransformedplants.TheGUSreportergenesystemhasmanyadvantagesincludingstableexpressionofE.coliGUSenzyme,nointerferencewithnormalplantmetabolism,andlowintrinsicGUSactivityinhigherplants.FDGlcUisconsideredtobeoneofthemostsensitivefluorogenicsubstratesavailablefordetectingbeta-glucuronidase.ThecolorlessandnonfluorescentFDGlcUishydrolyzedtohighlyfluorescentfluorescein,whichexhibitsexcellentspectralproperties(Ex/Em=492/520nm)thatmatchtheoptimaldetectionwindowofmostfluorescenceinstruments.Glucuronidase-catalyzedhydrolysisofFDGlcUcanbefollowedbyfluorescenceincreasearound520nm.Alternatively,FDGlcUcanalsobeusedtodetectglucuronidaseinachromogenicmodesincetheenzymaticproduct(fluorescein)exhibitsalargeextinctioncoefficient(closeto100,000cm-1mol-1).FDGlcUhasbeenusedforidentifyingGUS-positivecellswithfluorescencemicroscopyandflowcytometry.
SpectrumAdvancedSpectrumViewer

Sorry,yourbrowserdoesnotsupportinlineSVG.RelativeIntensity(%)100806040200Sorry,yourbrowserdoesnotsupportinlineSVG.
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References&Citations
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1.   HsiehJT.(2006)EnhancedtransgeneexpressioninurothelialcancergenetherapywithhistonedeacetylaseinhibitorOkegawaT,NutaharaK,PongRC,HigashiharaE,HsiehJT.DepartmentofUrology,UniversityofKyorin,Tokyo,Japan.UrolOncol,24,565.

2.   MorethK,RiesterD,HildmannC,HempelR,WegenerD,SchoberA,SchwienhorstA.(2006)Activesitetyrosineisessentialforamidohydrolasebutnotforesteraseactivityofaclass2histonedeacetylase-likebacterialenzyme.BiochemJ.

3.   BelienA,DeSchepperS,FlorenW,JanssensB,MarienA,KingP,VanDunJ,AndriesL,VoetenJ,BijnensL,JanicotM,ArtsJ.(2006)Real-timegeneexpressionanalysisinhumanxenograftsforevaluationofhistonedeacetylaseinhibitors.MolCancerTher,5,2317.

4.   Takahashi-FujigasakiJ,FujigasakiH.(2006)Histonedeacetylase(HDAC)4involvementinbothLewyandMarinescobodies.NeuropatholApplNeurobiol,32,562.

5.   OlaharskiAJ,JiZ,WooJY,LimS,HubbardAE,ZhangL,SmithMT.(2006)Thehistonedeacetylaseinhibitortrichostatinahasgenotoxiceffectsinhumanlymphoblastsinvitro.ToxicolSci,93,341.

6.   EyupogluIY,HahnenE,TrankleC,SavaskanNE,SiebzehnrublFA,BusleiR,LemkeD,WickW,FahlbuschR,BlumckeI.(2006)ExperimentaltherapyofmalignantgliomasusingtheinhibitorofhistonedeacetylaseMS-275.MolCancerTher,5,1248.

7.   FongPM,TianL,ChenZJ.(2006)ArABIdopsisthalianahistonedeacetylase1(AtHD1)islocalizedineuchromaticregionsanddemonstrateshistonedeacetylaseactivityinvitro.CellRes,16,479.

8.   OakesML,SiddiqiI,FrenchSL,VuL,SatoM,ArisJP,BeyerAL,NomuraM.(2006)RoleofhistonedeacetylaseRpd3inregulatingrRNAgenetranscriptionandnucleolarstructureinyeast.MolCellBiol,26,3889.

9.   WooHJ,LeeSJ,ChoiBT,ParkYM,ChoiYH.(2006)InductionofapoptosisandinhibitionoftelomeraseactivitybytrichostatinA,ahistonedeacetylaseinhibitor,inhumanleukemicU937cells.ExpMolPathol.

10.   HsiaoCH,LiW,LouTF,BaligaBS,PaceBS.(2006)Fetalhemoglobininductionbyhistonedeacetylaseinhibitorsinvolvesgenerationofreactiveoxygenspecies.ExpHematol,34,264.


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品牌介绍
美国AAT Bioquest Inc.(前身是ABD Bioquest,Inc.)是一家为从事生命科学研究、诊断研发及药物开发的科学家研发、生产和销售生物分析研究试剂和试剂盒的公司。公司致力于光谱学检测领域,包括吸收(颜色)、荧光和发光技术。AAT Bioquest的产品帮助全世界的科学家和生物医药研究者更好的了解生物化学、免疫学、细胞生物学和分子生物学等领域。AAT Bioquest会不断研发新产品,快速地丰富各个领域的产品。 1)提供反应探针和发光探针,生物素和端粒酶能够应用于标记药物小分子和生物聚合物,如蛋白、核酸以及其他碳水化合物; 2)研究并生产荧光和发光探针用于检测蛋白,核酸和活细胞; 3)不断推出新型的荧光和发光探针用于检测多种酶,特别是检测水解酶和氧化还原酶类; 4)致力于开发用于信号转导研究的试剂; 5)提供生理和神经探针,特别是钙离子指示剂和膜电位探针。
品牌分类
淋巴细胞信号传导 GPCR抗体 羰基活性生物素 细胞代谢 胺反应生物素 链霉亲和素结合物 生物素化抗IgGs 乙酰基特异性抗体 细胞骨架抗体
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