4000-520-616
欢迎来到免疫在线!(蚂蚁淘生物旗下平台)  请登录 |  免费注册 |  询价篮
aatbio(优势品牌)
主营:主营:研究并生产荧光和发光探针,信号转导研究的试剂
咨询热线电话
4000-520-616
当前位置: 首页 > 产品中心 > Other_biological_dyes > AAT Bioquest/MMP绿色与贸易;基质/13520/1mg
商品详细AAT Bioquest/MMP绿色与贸易;基质/13520/1mg
AAT Bioquest/MMP绿色与贸易;基质/13520/1mg
AAT Bioquest/MMP绿色与贸易;基质/13520/1mg
商品编号: 13520
品牌: aatbio
市场价: ¥143560.00
美元价: 86136.00
产地: 美国(厂家直采)
公司:
产品分类: 其他生物染料
公司分类: Other_biological_dyes
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Overview
PrinterFriendlyVersion

Ex/Em(nm)498/520
MW~2000
CAS#N/A
SolventDMSO
StorageF/D/L
CategoryEnzymeDetection
PeptidasesandProteases
RelatedMicroplateReaders
BiochemicalAssays
Thematrixmetalloproteinases(MMPs)constituteafamilyofzinc-dependentendopeptidasesthatfunctionwithintheextracellularmatrix.TheseenzymesareresponsIBLeforthebreakdownofconnectivetissuesandareimportantinboneremodeling,themenstrualcycleandrepairoftissuedamage.WhiletheexactcontributionofMMPstocertainpathologicalprocessesisdifficulttoassess,MMPsappeartoplayakeyroleinthedevelopmentofarthritisaswellasintheinvasionandmetastasisofcancer.MMPstendtohavemultiplesubstrates,withmostfamilymembershavingtheABIlitytodegradedifferenttypesofcollagenalongwithelastin,gelatinandfibronectin.ItisquitedifficulttofindasubstratethatisselectivetoasingleMMPenzyme.ThisFRETsubstrateisdesignedtomonitorthegeneralactivityofaMMPenzyme.ItcanalsobeusedtoscreeningMMPinhibitorswhenapurifiedMMPenzymeisused.ThisFRETsubstrateisbasedonourTF2/TQ2FRETpair.UponMMPhydrolysisthefluorescenceofMMPGreen™FRETpeptidesubstrateisincreasedsincetheTF2/TQ2FRETpairisseparated.ThefluorescenceincreaseisproportionaltotheMMPenzymeactivities.
SpectrumAdvancedSpectrumViewer

Sorry,yourbrowserdoesnotsupportinlineSVG.RelativeIntensity(%)100806040200Sorry,yourbrowserdoesnotsupportinlineSVG.
Sorry,yourbrowserdoesnotsupportinlineSVG.Sorry,yourbrowserdoesnotsupportinlineSVG.
Movemouseovergridtodisplaywavelength&intensityvalues.

300
400
500
600
700
800
900
Wavelength(nm)

References&Citations
CitationExplorer

Connexin43UpregulationbyDioscinInhibitsMelanomaProgressionviaSuppressingMalignancyandInducingM1Polarization
Authors:YuKou,LiyanJi,HaojiaWang,WenshengWang,HongmingZheng,JuanZou,LinxinLiu,XiaoxiaoQi,ZhongqiuLiu,BiaoyanDu
Journal:InternationalJournalofCancer(2017)

DACT2,anepigeneticstimulator,exertsdualefficacyforcolorectalcancerpreventionandtreatment
Authors:LinlinLu,YingWang,RilanOu,QianFeng,LiyanJi,HongmingZheng,YueGuo,XiaoxiaoQi,Ah-NgTonyKong,ZhongqiuLiu
Journal:Pharmacologicalresearch(2017)

ProbingCellAdhesionProfileswithaMicroscaleAdhesiveChoiceAssay
Authors:HarshaKittur,AndyTay,AveryHua,MinYu,DinoDiCarlo
Journal:BiophysicalJournal(2017):1858--1867

InhibitionofBETbromodomainattenuatesangiotensinIIinducedaBDominalaorticaneurysminApoE-/-mice
Authors:QiongDuan,XiaoxiaoMao,ChaonanLiao,HaoyangZhou,ZelinSun,XuDeng,QiuningHu,JunQi,GuogangZhang,HeHuang
Journal:InternationalJournalofCardiology(2016):428--432

Tissueinhibitorofmetalloproteinase1influencesvascularadaptationstochronicalterationsinbloodflow
Authors:ErinRMandel,CassandraUchida,EmmanuelNwadozi,ArminMakki,TaraLHaas
Journal:JournalofCellularPhysiology(2016)

β-adrenoceptorsareupregulatedinhumanmelanomaandtheiractivationreleasespro-tumOrigeniccytokinesandmetalloproteasesinmelanomacelllines
Authors:SilviaMoretti,DanielaMassi,ValentinaFarini,GiannaBaroni,MatteoParri,StefaniaInnocenti,RobertoCecchi,PaolaChiarugi
Journal:LaboratoryInvestigation(2013):279--290

MatrixRemodelingMaintainsEmbryonicStemCellSelf-RenewalbyActivatingStat3
Authors:LaralynneMPrzybyla,ThoroldWTheunissen,RudolfJaenisch,JoelVoldman
Journal:StemCells(2013):1097--1106

IdentificationandfunctionalvalidationofCDH11,PCSK6andSH3GL3asnovelgliomainvasion-associatedcandidategenes
Authors:SDelic,NLottmann,KJetschke,GReifenberger,MarkusJRiemenschneider
Journal:NeuropathologyandappliedneuroBIOLOGy(2012):201--212

EphA2inducesmetastaticgrowthregulatingamoeboidmotilityandclonogenicpotentialinprostatecarcinomacells
Authors:MariaLetiziaTaddei,MatteoParri,AdrianoAngelucci,FrancescaBianchini,ChiaraMarconi,ELISAGiannoni,GiovanniRaugei,MauroBologna,LidoCalorini,PaolaChiarugi
Journal:MolecularCancerResearch(2011):149--160


品牌介绍
美国AAT Bioquest Inc.(前身是ABD Bioquest,Inc.)是一家为从事生命科学研究、诊断研发及药物开发的科学家研发、生产和销售生物分析研究试剂和试剂盒的公司。公司致力于光谱学检测领域,包括吸收(颜色)、荧光和发光技术。AAT Bioquest的产品帮助全世界的科学家和生物医药研究者更好的了解生物化学、免疫学、细胞生物学和分子生物学等领域。AAT Bioquest会不断研发新产品,快速地丰富各个领域的产品。 1)提供反应探针和发光探针,生物素和端粒酶能够应用于标记药物小分子和生物聚合物,如蛋白、核酸以及其他碳水化合物; 2)研究并生产荧光和发光探针用于检测蛋白,核酸和活细胞; 3)不断推出新型的荧光和发光探针用于检测多种酶,特别是检测水解酶和氧化还原酶类; 4)致力于开发用于信号转导研究的试剂; 5)提供生理和神经探针,特别是钙离子指示剂和膜电位探针。
品牌分类
淋巴细胞信号传导 GPCR抗体 羰基活性生物素 细胞代谢 胺反应生物素 链霉亲和素结合物 生物素化抗IgGs 乙酰基特异性抗体 细胞骨架抗体
联络我们
服务热线:4000-520-616
(限工作日9:00-18:00)
QQ :1570468124
手机:18915418616