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主营:主营:研究并生产荧光和发光探针,信号转导研究的试剂
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当前位置: 首页 > 产品中心 > Fluorescent_dyes > AAT Bioquest/CLF [Cholyl-Lys-Fluorescein]/36701/1 mg
商品详细AAT Bioquest/CLF [Cholyl-Lys-Fluorescein]/36701/1 mg
AAT Bioquest/CLF [Cholyl-Lys-Fluorescein]/36701/1 mg
AAT Bioquest/CLF [Cholyl-Lys-Fluorescein]/36701/1 mg
商品编号: 36701
品牌: aatbio
市场价: ¥85560.00
美元价: 51336.00
产地: 美国(厂家直采)
公司:
产品分类: 荧光染料
公司分类: Fluorescent_dyes
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Overview
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Ex/Em(nm)492/516
MW926.12
CAS#N/A
SolventDMSO
StorageF/D/L
CategoryTransporters
BileAcidTransporters
RelatedCellFunctionalAnalysis
BiochemicalAssays
CLFisafluorescein-labeledbileacidanalogthatcloselyparallelsthecellularbindinganduptakepropertiesofcholicacidderivatives.Itisadivalent"unipolar"anionicfluorescentmonohydroxybilesaltanalogwithphysical,BIOLOGicalandcholestaticpropertiesthataresimilartothoseoflithocholate,glycolithocholateandtheirderivativesandthusoffersapotentiallyusefulprobeforstudyingmechanismsofmonohydroxybilesalt-inducedcholestasisatthehepatocellularlevel.CLFiscurrentlyusedasatoolforthevisualizationofbileacidtransportwithinlivertissue.
SpectrumAdvancedSpectrumViewer

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References&Citations
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1.   MitaS,SuzukiH,AkitaH,HayashiH,OnukiR,HofmannAF,SugiyamaY.(2006)InhibitionofbileacidtransportacrossNa+/taurocholatecotransportingpolypeptide(SLC10A1)andbilesaltexportpump(ABCB11)-coexpressingLLC-PK1cellsbycholestasis-inducingdrugs.DrugMetabDispos,34,1575.

2.   PerezLM,MilkiewiczP,EliasE,ColemanR,SanchezPozziEJ,RomaMG.(2006)Oxidativestressinducesinternalizationofthebilesaltexportpump,Bsep,andbilesaltsecretoryfailureinisolatedrathepatocytecouplets:aroleforproteinkinaseCandpreventionbyproteinkinaseA.ToxicolSci,91,150.

3.   WangW,SorokaCJ,MennoneA,RahnerC,HarryK,PypaertM,BoyerJL.(2006)RADIxinisrequiredtomaintainapicalcanalicularmembranestructureandfunctioninrathepatocytes.Gastroenterology,131,878.

4.   SidlerPfandlerMA,HochliM,InderbitzinD,MeierPJ,StiegerB.(2004)Smallhepatocytesinculturedeveloppolarizedtransporterexpressionanddifferentiation.JCellSci,117,4077.

5.   BeuersU,DenkGU,SorokaCJ,WimmerR,RustC,PaumgartnerG,BoyerJL.(2003)Taurolithocholicacidexertscholestaticeffectsviaphosphatidylinositol3-kinase-dependentmechanismsinperfusedratliversandrathepatocytecouplets.JBiolChem,278,17810.

6.   KidaM,ManoY,UenoY,KobayashiK,GotoJ,IshiiM,ShimosegawaT.(2003)Vectorialtransportofbileacidsinimmortalizedmousebileductcells.HepatolRes,27,151.

7.   RomanID,Fernandez-MorenoMD,FueyoJA,RomaMG,ColemanR.(2003)CyclosporinAinducedinternalizationofthebilesaltexportpumpinisolatedrathepatocytecouplets.ToxicolSci,71,276.

8.   MilkiewiczP,RomaMG,EliasE,ColemanR.(2002)Hepatoprotectionwithtauroursodeoxycholateandbetamuricholateagainsttaurolithocholateinducedcholestasis:involvementofsignaltransductionpathways.Gut,51,113.

9.   CrocenziFA,SanchezPozziEJ,PellegrinoJM,FavreCO,RodriguezGarayEA,MottinoAD,ColemanR,RomaMG.(2001)Beneficialeffectsofsilymarinonestrogen-inducedcholestasisintherat:astudyinvivoandinisolatedhepatocytecouplets.Hepatology,34,329.

10.   HolzingerF,KrahenbuhlL,SchteingartCD,Ton-NuHT,HofmannAF.(2001)Useofafluorescentbileacidtoenhancevisualizationofthebiliarytractandbileleaksduringlaparoscopicsurgeryinrabbits.SurgEndosc,15,209.


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品牌介绍
美国AAT Bioquest Inc.(前身是ABD Bioquest,Inc.)是一家为从事生命科学研究、诊断研发及药物开发的科学家研发、生产和销售生物分析研究试剂和试剂盒的公司。公司致力于光谱学检测领域,包括吸收(颜色)、荧光和发光技术。AAT Bioquest的产品帮助全世界的科学家和生物医药研究者更好的了解生物化学、免疫学、细胞生物学和分子生物学等领域。AAT Bioquest会不断研发新产品,快速地丰富各个领域的产品。 1)提供反应探针和发光探针,生物素和端粒酶能够应用于标记药物小分子和生物聚合物,如蛋白、核酸以及其他碳水化合物; 2)研究并生产荧光和发光探针用于检测蛋白,核酸和活细胞; 3)不断推出新型的荧光和发光探针用于检测多种酶,特别是检测水解酶和氧化还原酶类; 4)致力于开发用于信号转导研究的试剂; 5)提供生理和神经探针,特别是钙离子指示剂和膜电位探针。
品牌分类
淋巴细胞信号传导 GPCR抗体 羰基活性生物素 细胞代谢 胺反应生物素 链霉亲和素结合物 生物素化抗IgGs 乙酰基特异性抗体 细胞骨架抗体
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