4000-520-616
欢迎来到免疫在线!(蚂蚁淘生物旗下平台)  请登录 |  免费注册 |  询价篮
aatbio(优势品牌)
主营:主营:研究并生产荧光和发光探针,信号转导研究的试剂
咨询热线电话
4000-520-616
当前位置: 首页 > 产品中心 > Other_biological_dyes > AAT Bioquest/cAMP AM/20300/1毫克
商品详细AAT Bioquest/cAMP AM/20300/1毫克
AAT Bioquest/cAMP AM/20300/1毫克
AAT Bioquest/cAMP AM/20300/1毫克
商品编号: 20300
品牌: aatbio
市场价: ¥3900.00
美元价: 2340.00
产地: 美国(厂家直采)
公司:
产品分类: 其他生物染料
公司分类: Other_biological_dyes
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Overview
PrinterFriendlyVersion

Ex/Em(nm)None/None
MW401.27
CAS#N/A
SolventDMSO
StorageF/D/L
CategoryGPCR
cAMPGPCRAssays
RelatedDiagnosticMolecules
CellSignaling
BiochemicalAssays
cAMP-AMisthecell-permeantcAMP.AfterpermeationandmetabolicactivationbyesterasesthepolarcAMPisreleasedwhichistrappedinsidethecellandsubsequentlymetabolizedquickly,resultinginapulse-typesignal.cAMPisasecondmessenger,usedforintracellularsignaltransduction,suchastransferringintocellstheeffectsofhormoneslikeglucagonandadrenaline,whichcannotpassthroughtheplasmamembrane.Itisinvolvedintheactivationofproteinkinasesandregulatestheeffectsofadrenalineandglucagon.cAMPalsobindstoandregulatesthefunctionofionchannelssuchastheHCNchannelsandafewothercyclicnucleotide-bindingproteinssuchasEpac1andRAPGEF2.
References&Citations
PrinterFriendlyVersion

1.NicholsJM,MaiellaroI,ABI-JaoudeJ,CurciS,HoferAM.(2015)"Store-operated"cAMPsignalingcontributestoCa2+-activatedCl-secretioninT84coloniccells.AmJPhysiolGastrointestLiverPhysiol,309,G670.

2.ShangJ,LiJ,KellerMP,HohmeierHE,WangY,FengY,ZhouHH,ShenX,RabagliaM,SoniM,AttieAD,NewgardCB,ThornberryNA,HowardAD,ZhouYP.(2015)InductionofmiR-132andmiR-212ExpressionbyGlucagon-LikePeptide1(GLP-1)inRodentandHumanPancreaticbeta-Cells.MolEndocrinol,29,1243.

3.GerasimovaE,LebedevaJ,YakovlevA,ZefirovA,GiniatullinR,SitdikovaG.(2015)Mechanismsofhydrogensulfide(H2S)actiononsynaptictransmissionatthemouseneuromuscularjunction.Neuroscience,303,577.

4.GioinoP,MurrayBG,IanowskiJP.(2014)SEROtonintriggerscAMPandPKA-mediatedintracellularcalciumwavesinMalpighiantubulesofRhodniusprolixus.AmJPhysiolRegulIntegrCompPhysiol,307,R828.

5.BenesicA,SchwerdtG,HennemeierI,SauvantC,MildenbergerS,GekleM.(2014)ThenephrotoxicIfosfamide-metabolitechloroacetaldehydeinterfereswithrenalextracellularmatrixhomeostasis.CellPhysiolBiochem,33,1106.

6.AflakiM,QiXY,XiaoL,OrdogB,TadevosyanA,LuoX,MaguyA,ShiY,TardifJC,NattelS.(2014)ExchangeproteindirectlyactivatedbycAMPmediatesslowdelayed-rectifiercurrentremodelingbysustainedbeta-adrenergicactivationinguineapighearts.CircRes,114,993.

7.RajagopalM,ThomasSV,KathpaliaPP,ChenY,PaoAC.(2014)ProstaglandinE2induceschloridesecretionthroughcrosstalkbetweencAMPandcalciumsignalinginmouseinnermedullarycollectingductcells.AmJPhysiolCellPhysiol,306,C263.

8.IwaseK,IshiharaA,YoshimuraS,AndohY,KatoM,SekiN,MatsumotoE,HiwasaT,MullerD,FukunagaK,TakiguchiM.(2014)ThesecretograninIIgeneisasignalintegratorofglutamateanddopamineinputs.JNeuRochem,128,233.

9.RobertsOL,KamishimaT,Barrett-JolleyR,QuayleJM,DartC.(2013)ExchangeproteinactivatedbycAMP(Epac)inducesvascularrelaxationbyactivatingCa2+-sensitiveK+channelsinratmesentericartery.JPhysiol,591,5107.

10.MeijerLA,ZhouH,ChanOY,AltelaarAF,HennrichML,MohammedS,BosJL,HeckAJ.(2013)QuantitativeglobalphosphoproteomicsofhumanumbilicalveinendothelialcellsafteractivationoftheRapsignalingpathway.MolBiosyst,9,732.


ViewAllAsPDF
品牌介绍
美国AAT Bioquest Inc.(前身是ABD Bioquest,Inc.)是一家为从事生命科学研究、诊断研发及药物开发的科学家研发、生产和销售生物分析研究试剂和试剂盒的公司。公司致力于光谱学检测领域,包括吸收(颜色)、荧光和发光技术。AAT Bioquest的产品帮助全世界的科学家和生物医药研究者更好的了解生物化学、免疫学、细胞生物学和分子生物学等领域。AAT Bioquest会不断研发新产品,快速地丰富各个领域的产品。 1)提供反应探针和发光探针,生物素和端粒酶能够应用于标记药物小分子和生物聚合物,如蛋白、核酸以及其他碳水化合物; 2)研究并生产荧光和发光探针用于检测蛋白,核酸和活细胞; 3)不断推出新型的荧光和发光探针用于检测多种酶,特别是检测水解酶和氧化还原酶类; 4)致力于开发用于信号转导研究的试剂; 5)提供生理和神经探针,特别是钙离子指示剂和膜电位探针。
品牌分类
淋巴细胞信号传导 GPCR抗体 羰基活性生物素 细胞代谢 胺反应生物素 链霉亲和素结合物 生物素化抗IgGs 乙酰基特异性抗体 细胞骨架抗体
联络我们
服务热线:4000-520-616
(限工作日9:00-18:00)
QQ :1570468124
手机:18915418616